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Coditussin DAC and Remodulin

Determining the interaction of Coditussin DAC and Remodulin and the possibility of their joint administration.

Check result:
Coditussin DAC <> Remodulin
Relevance: 28.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using pseudoephedrine together with treprostinil. Using these medications together can make treprostinil less effective. You should be counseled to consult with your doctor before taking over-the-counter decongestants. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Concurrent administration of decongestants or vasoconstrictors may negate the vasodilatory effects of prostacyclin analogs in patients with pulmonary hypertension.

MANAGEMENT: The use of decongestants and vasoconstrictors should probably be avoided in patients with pulmonary hypertension. Patients should be counseled to consult with their physician before taking over-the-counter decongestants such as phenylephrine and pseudoephedrine.

References
  • Hardman JG, Gilman AG, Limbird LE eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th ed." New York, NY: McGraw-Hill (1995):
  • "Product Information. Remodulin (treprostinil)." United Therapeutics Corp, Silver Spring, MD.
  • "Product Information. Flolan (epoprostenol)." Glaxo Wellcome, Research Triangle Park, NC.
Coditussin DAC

Generic Name: codeine / guaifenesin / pseudoephedrine

Brand name: Cheratussin DAC, Coditussin DAC, Guaifenesin DAC, Lortuss EX, Tricode GF, Robitussin-DAC, Ryna-CX, Medent C, Novahistine Expectorant, Nucofed Expectorant, Tussar-2, Deproist with Codeine, Co-Histine Expectorant, Decohistine Expectorant, Dihistine Expectorant with Codeine, Dihistine Expectorant, Phenhist Expectorant, Halotussin DAC, Novadyne Expectorant, Nucochem Pediatric Expectorant, Nucochem Expectorant, Nuco-Tuss Pediatric Expectorant, Nucodine Pediatric, Cycofed Expectorant, KG-Fed Expectorant, Nucodine Expectorant, Deconsal C Expectorant, Guaiatussin DAC, Guiatuss DAC, Mytussin DAC, Guiatussin DAC, Cycofed Pediatric Expectorant, KG-Fed Pediatric Expectorant, Tussar SF, Phenylhistine Expectorant, Nuco-Tuss Expectorant, Nucochem, Dihistine, Gua PC, Codahistine Expectorant, GuaiFENesin DAC Liquid, Novagest with Codeine, Codafed, Codafed Pediatric, Ambifed-G CD, Maxifed CD, Ambifed-G CDX, Ambifed CDX, Maxifed-G CDX, Maxifed CDX, Suttar-2, Suttar SF, Z-Tuss E

Synonyms: n.a.

Remodulin

Generic Name: treprostinil

Brand name: Remodulin, Orenitram, Tyvaso, Tyvaso Refill Kit, Tyvaso Starter Kit

Synonyms: Remodulin (injection)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction