Cognex and Fluvoxamine ER Capsules
Determining the interaction of Cognex and Fluvoxamine ER Capsules and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using tacrine together with fluvoxaMINE. Using tacrine with fluvoxaMINE can increase your blood levels of tacrine. This combination may cause side effects such as nausea, vomiting, sweating and diarrhea. The risk of liver problems may also be increased. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The combined use of tacrine and fluvoxamine may result in elevated tacrine plasma concentrations. The mechanism may be due to the inhibition of CYP450 1A2 metabolism by fluvoxamine.
MANAGEMENT: This combination should be avoided if possible. If coadministration is necessary, monitor for side effects, such as nausea, vomiting, sweating and diarrhea. The risk of hepatotoxicity may be increased. Fluoxetine, a selective serotonin inhibitor that is not metabolized by 1A2 may be a safer alternative.
- Becquemont L, Ragueneau I, LeBot MA, Riche C, FunckBrentano C, Jaillon P "Influence of the CYP1A2 inhibitor fluvoxamine on tacrine pharmacokinetics in humans." Clin Pharmacol Ther 61 (1997): 619-27
Generic Name: fluvoxamine
Brand name: Luvox, Luvox CR
Synonyms: Fluvoxamine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cognex-Fluvoxamine Extended-Release Capsules
- Cognex-Fluvoxamine Maleate
- Cognex-Fluvoxamine Tablets
- Cognex-Fluxid
- Cognex-Fluzone
- Cognex-Fluzone 2013-2014 Formula
- Fluvoxamine ER Capsules-Col-Probenecid
- Fluvoxamine ER Capsules-Colace
- Fluvoxamine ER Capsules-Colace (Docusate Capsules and Tablets)
- Fluvoxamine ER Capsules-Colace (Docusate Liquid and Syrup)
- Fluvoxamine ER Capsules-Colace Microenema
- Fluvoxamine ER Capsules-Colace Pediatric