Col-Probenecid and Contac Cold+Flu Maximum Strength
Determining the interaction of Col-Probenecid and Contac Cold+Flu Maximum Strength and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Probenecid may slightly increase the therapeutic effects of acetaminophen. At usual doses, however, no intervention appears to be necessary.
- Kamali F, Fry JR, Bell GD "Salivary excretion of paracetamol in man." J Pharm Pharmacol 39 (1987): 150-2
- Abernethy DR, Greenblatt DJ, Ameer B, Shader RI "Probenecid impairment of acetaminophen and lorazepam clearance: direct inhibition of ether glucuronide formation." J Pharmacol Exp Ther 234 (1985): 345-9
Generic Name: probenecid
Brand name: Benemid
Synonyms: Probenecid
Generic Name: acetaminophen / chlorpheniramine / phenylephrine
Brand name: Alka-Seltzer Plus Cold, Comtrex Severe Cold & Sinus, Contac Cold+Flu Maximum Strength, Dristan Cold Multi Symptom Formula, Robitussin Nighttime Nasal Relief, Tylenol Allergy Multi-Symptom, Tylenol Children's Plus Cold, Tylenol Sinus Congestion Nighttime, Contac Cold/Flu Day & Night, Coricidin D Cold/Flu/Sinus, Dristan Cold, Medicidin-D, Onset Forte, Robitussin Peak Cold Nasal Relief, Super Cold Tabs, Super Strength Sinadrin, Tylenol Sinus Congestion/Pain, Cold Relief Plus, EQL Effervescent Plus Cold, GNP Cold Relief Plus, QC Cold Relief Plus
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Col-Probenecid-Contac Cold+Flu Non-Drowsy
- Col-Probenecid-Contac Cold/Flu Day & Night
- Col-Probenecid-Contac-D
- Col-Probenecid-Contrave
- Col-Probenecid-ConZip
- Col-Probenecid-Copanlisib
- Contac Cold+Flu Maximum Strength-Colace
- Contac Cold+Flu Maximum Strength-Colace (Docusate Capsules and Tablets)
- Contac Cold+Flu Maximum Strength-Colace (Docusate Liquid and Syrup)
- Contac Cold+Flu Maximum Strength-Colace Microenema
- Contac Cold+Flu Maximum Strength-Colace Pediatric
- Contac Cold+Flu Maximum Strength-Colazal