Colace and Sertraline Oral Concentrate

• Generic Name: docusate
• Dosage Forms: n.a.
• Other Brand Names: Colace, Colace Microenema, Enemeez Mini, Diocto, Doc-Q-Lace, Docu, Doculase, Docusil, Docusoft S, DocuSol, Dulcolax Stool Softener, Kao-Tin, Pedia-Lax Stool Softener, Phillips Stool Softener, Promolaxin, Silace, Surfak Stool Softener, Sur-Q-Lax, Dialose, DC-240, Kasof, DOK, Sulfalax Calcium, DOS, DSS, Modane Soft, Regulax SS, Dioeze, Aqualax, Dioctocal, Dioctosoftez, Dioctyn, Dionex, Docu Soft, Docucal, Calcium Stool Softener, Calube, D-S Caps, Ex-Lax Stool Softener, Genasoft, Doss-Relief, Fleet Sof-Lax, Colace Micro-Enema, Correctol Softgel Extra Gentle, Therevac-SB, Octycine-100, Octycine-250, Sulfolax, Kaopectate Stool Softener, Vacuant, Docuprene, DocuSol Kids, Colace Clear, Docusate Mini, Surfak

Colace (docusate) is a stool softener. It makes bowel movements softer and easier to pass.

Colace is used to treat or prevent occasional constipation, and to reduce pain or rectal damage caused by hard stools or by straining during bowel movements.

Colace may also be used for purposes not listed in this medication guide.

• Generic Name: sertraline
• Dosage Forms: oral solution, concentrate
• Other Brand Names: Zoloft

Management of major depressive disorder.

Efficacy in hospital settings not established.

APA states that effectiveness of antidepressants is generally comparable between and within classes of medications, including SSRIs, SNRIs, TCAs, MAOIs, and other antidepressants (e.g., bupropion, mirtazapine, trazodone). Choose antidepressant based mainly on patient preference; nature of prior response to medication; safety, tolerability, and anticipated adverse effects; concurrent psychiatric and medical conditions; and specific properties of the medication (e.g., half-life, actions on CYP450 enzymes, other drug interactions). For most patients, an SSRI, SNRI, mirtazapine, or bupropion is considered optimal. Consult APA’s Practice Guidelines for the Treatment of Patients with Major Depressive Disorder for additional information.

Management of OCD; reduces but does not completely eliminate obsessions and compulsions.

Management of panic disorder with or without agoraphobia.

Management of PTSD; more effective in women than in men.

Not effective for combat- or war-related PTSD.

Management of PMDD; improves symptoms (e.g., depressed mood, premenstrual anger/irritability) and functional impairment (e.g., difficulty in concentrating, lethargy) associated with this disorder.

Efficacy when used in conjunction with oral contraceptives for the treatment of PMDD is unknown.

Management of social phobia (social anxiety disorder).

Has been used in the management of premature ejaculation.

Has been used in the management of vascular headaches with equivocal efficacy.