Colestipol and InnoPran XL

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this interaction is not currently available.MONITOR: Coadministration with colestipol or cholestyramine may result in an up to 50% decrease in propranolol plasma concentrations. The proposed mechanism is binding of propranolol by these resins. However, clinical data evaluating this interaction are limited. MANAGEMENT: Until more information is available, caution is advised if colestipol or cholestyramine are used concomitantly with propranolol. Propranolol should be administered at least 1 to 2 hours before or 4 to 6 hours after cholestyramine or colestipol administration. Dosage adjustments as well as clinical monitoring of propranolol should be considered whenever colestipol or cholestyramine is added to or withdrawn from therapy. References "Product Information. Inderal (propranolol)." Wyeth-Ayerst Laboratories, Philadelphia, PA. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 Cerner Multum, Inc. "Australian Product Information." O 0 "Product Information. Colestid (colestipol HCI)." Pharmacia and Upjohn, Kalamazoo, MI. Agencia Española de Medicamentos y Productos Sanitarios Healthcare "Centro de información online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]): "Product Information. Questran (cholestyramine)." Par Pharmaceutical Inc, Chestnut Ridge, NY. Hibbard DM, Peters JR, Hunninghake DB "Effects of cholestyramine and colestipol on the plasma concentrations of propranolol." Br J Clin Pharmacol 18 (1984): 337-42 View all 7 references

MONITOR: Coadministration with colestipol or cholestyramine may result in an up to 50% decrease in propranolol plasma concentrations. The proposed mechanism is binding of propranolol by these resins. However, clinical data evaluating this interaction are limited.

MANAGEMENT: Until more information is available, caution is advised if colestipol or cholestyramine are used concomitantly with propranolol. Propranolol should be administered at least 1 to 2 hours before or 4 to 6 hours after cholestyramine or colestipol administration. Dosage adjustments as well as clinical monitoring of propranolol should be considered whenever colestipol or cholestyramine is added to or withdrawn from therapy.

Colestipol

Generic Name: colestipol

Brand name: Colestid, Colestid Flavored

Synonyms: n.a.

What is Colestipol?

InnoPran XL

Generic Name: propranolol

Brand name: Hemangeol, Inderal LA, Inderal XL, InnoPran XL, Inderal, InnoPran XL

Synonyms: n.a.

What is InnoPran XL?