Colistimethate Injection and Fludrocortisone Acetate

• Generic Name: colistimethate
• Dosage Forms: n.a.
• Other Brand Names: Coly Mycin M

Colistimethate injection is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines called antibiotics that works by killing bacteria or preventing their growth. However, colistimethate will not work for colds, flu, or other virus infections.

Colistimethate is to be given only by or under the direct supervision of your doctor.

• Generic Name: fludrocortisone
• Dosage Forms: n.a.
• Other Brand Names: Florinef Acetate

Used for oral mineralocorticoid replacement therapy; use is contraindicated in all conditions except those that require a high degree of mineralocorticoid activity.

Partial replacement therapy, in combination with hydrocortisone or cortisone, for treatment of primary and secondary adrenocortical insufficiency in Addison’s disease after electrolyte balance has been restored.

Hydrocortisone or cortisone (in conjunction with liberal salt intake) usually is the corticosteroid of choice for replacement therapy; concomitant administration of fludrocortisone may be required in some patients.

Treatment of salt-losing congenital adrenogenital syndrome after electrolyte balance has been restored.

Has been used with some success to increase SBP and DBP in patients with severe, chronic postural hypotension (e.g., secondary to autonomic dysfunction, levodopa therapy) that does not respond adequately to nondrug therapy.