Collagenase Santyl and Dantrium

• Generic Name: collagenase clostridium histolyticum
• Dosage Forms: ointment
• Other Brand Names: Xiaflex

Collagenase clostridium histolyticum is made from a mixture of proteins derived from a certain bacteria.

Collagenase clostridium histolyticum is used to treat Dupuytren's contracture in adults. This condition causes an abnormal thickening of the tissue in the palm of the hand. This condition may get worse over time and form a "cord" in your palm, causing a permanent bend in your finger.

Collagenase clostridium histolyticum is also used to treat a related condition called Peyronie's disease in adult men. This condition causes scar tissue or "plaque" to develop under the skin of the penis, resulting in an abnormal curving of the penis during erection.

Collagenase clostridium histolyticum is available for Peyronie's disease only from a certified pharmacy under a special program called Xiaflex REMS. You must be registered in the program and understand the risks of taking collagenase clostridium histolyticum.

Collagenase clostridium histolyticum may also be used for purposes not listed in this medication guide.

• Generic Name: dantrolene
• Dosage Forms: capsule
• Other Brand Names: Dantrium, Dantrium Intravenous, Revonto, Ryanodex

Dantrium is a muscle relaxer.

Dantrium is used to treat muscle spasticity (stiffness and spasms) caused by conditions such as a spinal cord injury, stroke, cerebral palsy, or multiple sclerosis.

Dantrium is also used to prevent muscle stiffness and spasms caused by malignant hyperthermia (a rapid rise in body temperature and severe muscle contractions) that can occur during surgery with certain types of anesthesia.

Dantrium may also be used for purposes not listed in this medication guide.