Collagenase Santyl and Tazorac

• Generic Name: collagenase clostridium histolyticum
• Dosage Forms: ointment
• Other Brand Names: Xiaflex

Collagenase clostridium histolyticum is made from a mixture of proteins derived from a certain bacteria.

Collagenase clostridium histolyticum is used to treat Dupuytren's contracture in adults. This condition causes an abnormal thickening of the tissue in the palm of the hand. This condition may get worse over time and form a "cord" in your palm, causing a permanent bend in your finger.

Collagenase clostridium histolyticum is also used to treat a related condition called Peyronie's disease in adult men. This condition causes scar tissue or "plaque" to develop under the skin of the penis, resulting in an abnormal curving of the penis during erection.

Collagenase clostridium histolyticum is available for Peyronie's disease only from a certified pharmacy under a special program called Xiaflex REMS. You must be registered in the program and understand the risks of taking collagenase clostridium histolyticum.

Collagenase clostridium histolyticum may also be used for purposes not listed in this medication guide.

• Generic Name: tazarotene topical
• Dosage Forms: gel
• Other Brand Names: Avage, Fabior, Tazorac

Tazorac (for use on skin) is a compound similar to vitamin A. It helps the skin to renew itself more quickly and may improve the appearance and texture of skin.

The Avage brand of tazarotene cream is used to reduce the appearance of fine wrinkles on the face, mottled light and dark skin patches on the face, and benign facial lentigines (non-cancerous freckles) in adults and adolescents who are at least 17 years old.

The Fabior and Tazorac brands of tazarotene topical are used to treat acne vulgaris in adults and adolescents who are at least 12 years old.

Tazorac is also used to treat plaque psoriasis (raised, silvery flaking of the skin) in adults.

Tazorac may also be used for purposes not listed in this medication guide.