Comfort Pac w/Tizanidine and Cubicin, Cubicin RF

• Generic Name: tizanidine
• Dosage Forms: n.a.
• Other Brand Names: Zanaflex

Tizanidine is used to help relax certain muscles in your body. It relieves spasms, cramping, and tightness of the muscles caused by medical problems, such as multiple sclerosis or certain injuries to the spine. Tizanidine does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition.

Tizanidine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects.

This medicine is available only with your doctor's prescription.

• Generic Name: daptomycin
• Dosage Forms: n.a.
• Other Brand Names: Cubicin, Cubicin RF

Treatment of complicated skin and skin structure infections caused by susceptible Staphylococcus aureus (including methicillin-resistant S. aureus [MRSA; also known as oxacillin-resistant S. aureus or ORSA]), Streptococcus pyogenes (group A β-hemolytic streptococci, GAS), S. agalactiae (group B streptococci, GBS), S. dysgalactiae subsp. equisimilis, and Enterococcus faecalis (vancomycin-susceptible strains only).

Bacteremia and Endocarditis

Treatment of bacteremia (blood stream infection) caused by susceptible S. aureus (including MRSA).

Also used for treatment of S. aureus bacteremia in patients with right-sided infective endocarditis. Efficacy not established in patients with left-sided infective endocarditis caused by S. aureus; limited data suggest a poor outcome in such patients despite daptomycin treatment.

Not studied in patients with prosthetic valve endocarditis.