Complement C1 esterase inhibitor and Pioglitazone Hydrochloride

• Generic Name: C1 esterase inhibitor (human)
• Dosage Forms: n.a.
• Other Brand Names: Berinert, Cinryze, Haegarda, Ruconest

Complement C1 esterase inhibitor is a man-made form of a protein in blood that helps control swelling in the body. People with a condition called hereditary angioedema do not have enough of this protein. Hereditary angioedema can cause attacks of swelling and symptoms such as stomach problems or trouble breathing.

Complement C1 esterase inhibitor is used in people with hereditary angioedema. Berinert is used to treat attacks of angioedema. Cinryze and Haegarda are used to prevent attacks of angioedema.

Complement C1 esterase inhibitor may also be used for purposes not listed in this medication guide.

• Generic Name: pioglitazone
• Dosage Forms: n.a.
• Other Brand Names: Actos

Used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise to improve glycemic control in patients with type 2 (noninsulin-dependent) diabetes mellitus (NIDDM). Should be added to, not substituted for, other antidiabetic agents in patients whose NIDDM is not adequately controlled by these agents.

May be added to glyburide/metformin fixed combination therapy if hyperglycemia is not adequately controlled with the fixed combination. May be used in combination with repaglinide if hyperglycemia is not adequately controlled with diet, exercise, and monotherapy with another oral antidiabetic agent.

Not effective as sole therapy for type 1 diabetes mellitus or diabetic ketoacidosis.