Complement C1 esterase inhibitor and Simponi

• Generic Name: C1 esterase inhibitor (human)
• Dosage Forms: n.a.
• Other Brand Names: Berinert, Cinryze, Haegarda, Ruconest

Complement C1 esterase inhibitor is a man-made form of a protein in blood that helps control swelling in the body. People with a condition called hereditary angioedema do not have enough of this protein. Hereditary angioedema can cause attacks of swelling and symptoms such as stomach problems or trouble breathing.

Complement C1 esterase inhibitor is used in people with hereditary angioedema. Berinert is used to treat attacks of angioedema. Cinryze and Haegarda are used to prevent attacks of angioedema.

Complement C1 esterase inhibitor may also be used for purposes not listed in this medication guide.

• Generic Name: golimumab
• Dosage Forms: injection, solution
• Other Brand Names: Simponi, Simponi SmartJect, Simponi Aria

Simponi (golimumab) reduces the effects of a substance in the body that can cause inflammation.

Simponi is used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, or ulcerative colitis.

Simponi is sometimes used with another medicine called methotrexate (Rheumatrex, Trexall).