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Comtrex Flu Therapy Day/Night and Oxytocin

Determining the interaction of Comtrex Flu Therapy Day/Night and Oxytocin and the possibility of their joint administration.

Check result:
Comtrex Flu Therapy Day/Night <> Oxytocin
Relevance: 13.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using oxytocin together with phenylephrine may cause significant elevations in blood pressure and increase the risk of hypertension. Blood pressure and heart rate should be closely monitored if these medications are used together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Concomitant use of oxytocic agents with sympathomimetic amines may increase the risk of hypertension due to additive vasoconstrictive effects. Severe hypertension and headache have been reported when oxytocin was given 3 to 4 hours following prophylactic administration of a vasoconstrictor in conjunction with caudal block anesthesia.

MANAGEMENT: Close monitoring of blood pressure is recommended during coadministration.

References
  • "Product Information. Syntocinon (oxytocin)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Comtrex Flu Therapy Day/Night

Generic Name: acetaminophen / chlorpheniramine / phenylephrine

Brand name: Allergy Multi-Symptom, Allergy Multi-Symptom Daytime, Comtrex Flu Therapy Day/Night, Comtrex Severe Cold & Sinus, Contac Cold+Flu Maximum Strength, Gendecon, Protid, Dryphen, Comtrex Flu Therapy, Sinus Congestion & Pain Nighttime, Allergy Relief Multi-Symptom, Tylenol Sinus Congestion-Pain Cool Burst, Relief-PE, Contact Cold and Flu Night, Cold Relief Plus, EQL Effervescent Plus Cold, GNP Cold Relief Plus, QC Cold Relief Plus

Synonyms: n.a.

Oxytocin

Generic Name: oxytocin

Brand name: Pitocin, Syntocinon

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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