Conivaptan Hydrochloride and Guaifenex

• Generic Name: conivaptan
• Dosage Forms: n.a.
• Other Brand Names: Vaprisol

Used to increase serum sodium concentrations in hospitalized patients with euvolemic or hypervolemic hyponatremia. Use in patients with hypervolemic hyponatremia associated with heart failure only after consideration of other treatment options; limited data on safety in this patient population. (See CHF under Cautions.)

Not indicated for the treatment of hypovolemic hyponatremia.

Use of conivaptan to increase serum sodium concentrations has not been established to provide symptomatic benefit to patients.

Not indicated for the treatment of CHF; efficacy not established for this indication.

• Generic Name: guaifenesin / phenylephrine / phenylpropanolamine
• Dosage Forms: n.a.
• Other Brand Names:

  Ami-Tex, Banex, Dura-Gest, Duratex, Enomine, Entex, Fentex, Guaifenex, Phenylfenesin, Quintex

Phenylpropanolamine, an ingredient in this product, has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Drink plenty of extra fluids while taking this medication.

Do not crush or chew the tablets. Swallow them whole or break them in half where they are scored to make them easier to swallow if needed.