Contac Cold/Flu Day & Night and Diflunisal
Determining the interaction of Contac Cold/Flu Day & Night and Diflunisal and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Acetaminophen serum concentrations may be elevated by as much as 50% during concomitant therapy with diflunisal in normal subjects. The clinical significance of this finding is unknown. Because elevated acetaminophen levels are associated with hepatotoxicity, the manufacturer recommends caution when this combination is used.
- "Product Information. Dolobid (diflunisal)." Merck & Co, Inc, West Point, PA.
Generic Name: acetaminophen / chlorpheniramine / phenylephrine
Brand name: Alka-Seltzer Plus Cold, Comtrex Severe Cold & Sinus, Contac Cold+Flu Maximum Strength, Dristan Cold Multi Symptom Formula, Robitussin Nighttime Nasal Relief, Tylenol Allergy Multi-Symptom, Tylenol Children's Plus Cold, Tylenol Sinus Congestion Nighttime, Contac Cold/Flu Day & Night, Coricidin D Cold/Flu/Sinus, Dristan Cold, Medicidin-D, Onset Forte, Robitussin Peak Cold Nasal Relief, Super Cold Tabs, Super Strength Sinadrin, Tylenol Sinus Congestion/Pain, Cold Relief Plus, EQL Effervescent Plus Cold, GNP Cold Relief Plus, QC Cold Relief Plus
Synonyms: Acetaminophen, chlorpheniramine, and phenylephrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Diflunisal-Copanlisib
- Diflunisal-Copanlisib Intravenous
- Diflunisal-Copaxone