Copegus and Tranylcypromine Sulfate

• Generic Name: ribavirin
• Dosage Forms: tablet, film coated
• Other Brand Names: Copegus, Ribasphere, Rebetol, RibaPak, RibaTab, Virazole, RibaPak 600, Moderiba, Moderiba 800 Dose Pack, Moderiba 1200 Dose Pack, Moderiba 1000 Dose Pack, Moderiba 600 Dose Pack

• It is used to treat hepatitis C infection.
• This medicine may be used along with interferon or peginterferon. If you are using one of these drugs, read the patient fact sheet that comes with it.

• Generic Name: tranylcypromine
• Dosage Forms: n.a.
• Other Brand Names: Parnate

Treatment of major depressive disorder without melancholia.

Efficacy in major depressive disorder with melancholia (endogenous features) not established.

MAO inhibitors appear particularly effective in treatment of major depressive disorder with atypical features, although other antidepressants (e.g., SSRIs) may initially be used because of their more favorable adverse effect profile.

Because of potential for serious adverse effects and necessity of dietary restrictions, MAO inhibitors (e.g., phenelzine, tranylcypromine) generally are not used as initial therapy for major depressive disorder, but are reserved for carefully selected patients who can be closely supervised and who have depression refractory to other antidepressants (e.g., SSRIs, SNRIs, TCAs) or in whom other therapies are contraindicated.