CoQ10 coenzyme Q-10 and Ifex/Mesnex Kit

• Generic Name: ubiquinone
• Dosage Forms: n.a.
• Other Brand Names: Coenzyme Q10, CoQ10, elppa CoQ10, LiQsorb, Q-Sorb Co Q-10, QuinZyme, Co-Q10, NutraDrops, Liquid Co-Q10, Co Q-10, Coenzyme Q10, LiQ-10

CoQ10 is a vitamin-like substance that is made naturally in the body. This medicine is also known as Coenzima, Ubidcarenone, Ubidécarénone, and Ubiquinol.

CoQ10 is likely effective in alternative medicine as an aid in treating coenzyme Q-10 deficiency, or reducing the symptoms of mitochondrial disorders (conditions that affect energy-production in the cells of the body).

CoQ10 is also possibly effective in preventing migraine headaches, lowering blood pressure, preventing a second heart attack, or slowing the progression of early Parkinson's disease. This medicine is also possibly effective in improving symptoms in people with congestive heart failure, nerve problems caused by diabetes, Huntington's disease, muscular dystrophy, or macular degeneration (age-related vision loss).

CoQ10 has also been used to treat Alzheimer's disease, high cholesterol, or amyotrophic lateral sclerosis (Lou Gehrig's disease). However, research has shown that this medicine may not be effective in treating these conditions.

Research also has shown that CoQ10 is not likely to be effective in increasing athletic performance.

Other uses not proven with research have included treating asthma, COPD, cancer, diabetes, certain heart problems, fibromyalgia, hepatitis C, kidney problems, high blood pressure during pregnancy, muscle problems caused by taking "statin" cholesterol medicine, and other conditions.

CoQ10 is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

CoQ10 may also be used for purposes not listed in this product guide.

• Generic Name: ifosfamide
• Dosage Forms: n.a.
• Other Brand Names: Ifex

Component of various chemotherapeutic regimens as third-line therapy for recurrent or refractory germ cell testicular cancer (designated an orphan drug by FDA for this use).

Component of various chemotherapeutic regimens in conjunction with surgery and/or radiation therapy in the treatment of various soft tissue sarcomas (designated an orphan drug by FDA for this use).

Used alone or in conjunction with other drugs (e.g., etoposide) for treatment of localized, metastatic, and recurrent osteosarcoma (designated an orphan drug by FDA for this use).

Used alone or in combination with other antineoplastic agents for treatment of advanced or metastatic bladder cancer.

Treatment of small cell lung cancer as part of a combination regimen.

Component of various combination regimens (e.g., cisplatin and ifosfamide with or without bleomycin) for the treatment of metastatic or recurrent cervical cancer.

Used alone or in conjunction with other antineoplastic agents for second-line (salvage) therapy in patients with advanced or recurrent ovarian carcinoma.

Treatment of advanced small noncleaved cell lymphoma (Burkitt’s and non-Burkitt’s) in children as part of a combination regimen.