Cordarone injection and Isoptin SR
Determining the interaction of Cordarone injection and Isoptin SR and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:The use of amiodarone with verapamil may have additive effects when taken together. While this combination may be useful in some situations contact your doctor if you have a reduced heart rate, dizziness, fainting, or headaches. Your blood pressure may need to be checked more frequently. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using your medications without first talking to your doctor first.
Professional:MONITOR CLOSELY: Amiodarone and diltiazem or verapamil may have additive pharmacodynamic effects when administered concurrently. Sinus arrest, reduced myocardial contractility, and hypotension could result.
MANAGEMENT: The patient's hemodynamic and electrocardiographic status should be closely monitored, especially during amiodarone loading.
- Kerin NZ, Aragon E, Faitel K, Frumin H, Rubenfire M "Long-term efficacy and toxicity of high- and low-dose amiodarone regimens." J Clin Pharmacol 29 (1989): 418-23
- Wilson JS, Podrid PJ "Side effects from amiodarone." Am Heart J 121 (1991): 158-71
- Lee TH, Friedman PL, Goldman L, Stone PH, Antman EM "Sinus arrest and hypotension with combined amiodarone-diltiazem therapy." Am Heart J 109 (1985): 163-4
- Lee TH, Friedman PL, Goldman L, Stone PH, Antman EM "Sinus arrest and hypotension with combined amiodarone-diltiazem therapy." Am Heart J 109 (1985): 163-4
Generic Name: amiodarone
Brand name: Cordarone, Pacerone, Nexterone
Synonyms: Cordarone
Generic Name: verapamil
Brand name: Calan SR, Isoptin SR, Calan, Verelan, Isoptin, Isoptin IV, Covera-HS, Verelan PM
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cordarone injection-Isopto Atropine
- Cordarone injection-Isopto Atropine Ophthalmic
- Cordarone injection-Isopto Atropine Ophthalmic Solution
- Cordarone injection-Isopto Carbachol
- Cordarone injection-Isopto Carbachol Ophthalmic Solution
- Cordarone injection-Isopto Carpine
- Isoptin SR-Cordarone IV Intravenous
- Isoptin SR-Cordran
- Isoptin SR-Cordran (Flurandrenolide Cream and Ointment)
- Isoptin SR-Cordran (Flurandrenolide Lotion)
- Isoptin SR-Cordran Lotion
- Isoptin SR-Cordran SP