Coricidin Night Time Cold Relief and Hydroxyprogesterone Caproate Injection
Determining the interaction of Coricidin Night Time Cold Relief and Hydroxyprogesterone Caproate Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:HYDROXYprogesterone may reduce the blood levels and effects of acetaminophen. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with hydroxyprogesterone may decrease the plasma concentrations of drugs that are metabolized by CYP450 1A2, 2A6, and/or 2B6. An in vitro study using human liver microsomes and CYP isoform-selective substrates indicated that hydroxyprogesterone caproate can increase the metabolic rate of CYP450 1A2, 2A6, and 2B6 by approximately 80%, 150%, and 80%, respectively. The clinical significance has not been determined.
MANAGEMENT: Pharmacologic effects and/or serum concentrations of the coadministered drug should be monitored more closely whenever hydroxyprogesterone is added to or withdrawn from therapy, and the dosage adjusted if an interaction is suspected.
- "Product Information. Makena (hydroxyprogesterone)." Ther-Rx Corporation, Bridgeton, MO.
Generic Name: acetaminophen / diphenhydramine
Brand name: Aceta-Gesic, Coricidin Night Time Cold Relief, Excedrin PM, Headache Relief PM, Legatrin PM, Mapap PM, Midol PM, Night Time Pain, Pain Relief PM Extra Strength, Percogesic Extra Strength, Tylenol Cold Relief Nighttime, Tylenol PM, Tylenol Sore Throat Nighttime, Unisom with Pain Relief, Tylenol Extra Strength PM, Bayer Select Max Strength Night Time Pain, Genapap PM, Excedrin PM Caplet, Sominex Pain Relief Formula, Tylenol Severe Allergy Caplet, Anacin PM. Aspirin Free, Tylenol Extra Strength PM Vanilla, Tylenol Cold Relief Caplet, Tylenol Cold Relief Nighttime Caplet, Tylenol Extra Strength PM Rapid Release Gelcaps, Excedrin PM Express, Percogesic Original Strength, Tylenol Cold Relief, Tylenol Severe Allergy
Synonyms: n.a.
Generic Name: hydroxyprogesterone
Brand name: Makena, Makena Auto-Injector, Hylutin, Delta-Lutin, Duralutin, Hyprogesterone, Prodrox
Synonyms: Hydroxyprogesterone injection, Hydroxyprogesterone Caproate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Coricidin Night Time Cold Relief-Hydroxyprogesterone Caproate Injection (Makena)
- Coricidin Night Time Cold Relief-Hydroxyprogesterone injection
- Coricidin Night Time Cold Relief-Hydroxyprogesterone Intramuscular
- Coricidin Night Time Cold Relief-Hydroxyquinoline vaginal
- Coricidin Night Time Cold Relief-Hydroxyurea
- Coricidin Night Time Cold Relief-Hydroxyurea Capsules 200 mg, 300 mg, 400 mg
- Hydroxyprogesterone Caproate Injection-Corifact
- Hydroxyprogesterone Caproate Injection-Corlanor
- Hydroxyprogesterone Caproate Injection-Corlanor (Ivabradine Oral Solution)
- Hydroxyprogesterone Caproate Injection-Corlanor (Ivabradine Tablets)
- Hydroxyprogesterone Caproate Injection-Corlopam
- Hydroxyprogesterone Caproate Injection-Cormax