Coricidin Night Time Cold Relief and Lorcaserin Extended-Release Tablets
Determining the interaction of Coricidin Night Time Cold Relief and Lorcaserin Extended-Release Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Lorcaserin may increase the blood levels and effects of diphenhydrAMINE. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience increased side effects or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with lorcaserin may increase the plasma concentrations of drugs that are primarily metabolized by CYP450 2D6. The mechanism is decreased clearance due to inhibition of CYP450 2D6 activity by lorcaserin. In a study consisting of 21 CYP450 2D6 extensive metabolizers, administration of the probe substrate dextromethorphan in combination with lorcaserin 10 mg twice daily for 4 days increased dextromethorphan peak concentrations (Cmax) by approximately 76% and systemic exposure (AUC) by approximately 2-fold.
MANAGEMENT: Caution is advised if lorcaserin is prescribed concomitantly with medications that undergo metabolism by CYP450 2D6, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever lorcaserin is added to or withdrawn from therapy.
- "Product Information. Belviq (lorcaserin)." Eisai Inc, Teaneck, NJ.
Generic Name: acetaminophen / diphenhydramine
Brand name: Aceta-Gesic, Coricidin Night Time Cold Relief, Excedrin PM, Headache Relief PM, Legatrin PM, Mapap PM, Midol PM, Night Time Pain, Pain Relief PM Extra Strength, Percogesic Extra Strength, Tylenol Cold Relief Nighttime, Tylenol PM, Tylenol Sore Throat Nighttime, Unisom with Pain Relief, Tylenol Extra Strength PM, Bayer Select Max Strength Night Time Pain, Genapap PM, Excedrin PM Caplet, Sominex Pain Relief Formula, Tylenol Severe Allergy Caplet, Anacin PM. Aspirin Free, Tylenol Extra Strength PM Vanilla, Tylenol Cold Relief Caplet, Tylenol Cold Relief Nighttime Caplet, Tylenol Extra Strength PM Rapid Release Gelcaps, Excedrin PM Express, Percogesic Original Strength, Tylenol Cold Relief, Tylenol Severe Allergy
Synonyms: n.a.
Generic Name: lorcaserin
Brand name: Belviq, Belviq XR
Synonyms: Lorcaserin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Coricidin Night Time Cold Relief-Lorcaserin Hydrochloride
- Coricidin Night Time Cold Relief-Lorcaserin Tablets
- Coricidin Night Time Cold Relief-Lorcet
- Coricidin Night Time Cold Relief-Lorcet Plus
- Coricidin Night Time Cold Relief-Lorcet Tablets
- Coricidin Night Time Cold Relief-Lorlatinib
- Lorcaserin Extended-Release Tablets-Corifact
- Lorcaserin Extended-Release Tablets-Corlanor
- Lorcaserin Extended-Release Tablets-Corlanor (Ivabradine Oral Solution)
- Lorcaserin Extended-Release Tablets-Corlanor (Ivabradine Tablets)
- Lorcaserin Extended-Release Tablets-Corlopam
- Lorcaserin Extended-Release Tablets-Cormax