Corifact and Duloxetine

• Generic Name: factor XIII
• Dosage Forms: injection
• Other Brand Names: Corifact, Tretten

Corifact (factor XIII) is used to prevent bleeding episodes in people with a hereditary bleeding disorder caused by a deficiency of Factor XIII.

Factor XIII (thirteen) is a naturally occurring protein in the blood that helps blood to clot. A lack of clotting factors can cause uncontrolled bleeding, as the blood is unable to clot properly. This medicine works by temporarily raising levels of these factor XIII in the blood to aid in clotting.

Corifact will not treat a bleeding episode that has already begun.

Corifact may also be used for purposes not listed in this medication guide.

• Generic Name: duloxetine
• Dosage Forms: n.a.
• Other Brand Names: Cymbalta, Irenka, Drizalma Sprinkle

Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Duloxetine affects chemicals in the brain that may be unbalanced in people with depression.

Duloxetine is used to treat major depressive disorder in adults. It is also used to treat general anxiety disorder in adults and children who are at least 7 years old.

Duloxetine is also used in adults to treat fibromyalgia (a chronic pain disorder), or chronic muscle or joint pain (such as low back pain and osteoarthritis pain).

Duloxetine is also used to treat pain caused by nerve damage in adults with diabetes (diabetic neuropathy).