Corlanor (Ivabradine Tablets) and Venclexta

• Generic Name: ivabradine
• Dosage Forms: tablet, film coated
• Other Brand Names: Corlanor

• It is used to treat heart failure (weak heart).
• It is used in certain patients with heart failure to lower the chance of having to go to the hospital for heart failure that gets worse.
• It may be given to you for other reasons. Talk with the doctor.

• Generic Name: venetoclax
• Dosage Forms: tablets
• Other Brand Names: Venclexta, Venclexta Starting Pack

Venclexta (venetoclax) inhibits a certain protein in cancer cells (abnormal lymphocytes produced in chronic lymphocytic leukemia) that helps keep those cells alive and makes them resistant to chemotherapy. Venetoclax binds to this protein, which helps kill the cancerous lymphocytes in blood and bone marrow.

Venclexta is used to treat chronic lymphocytic leukemia (CLL) or small lymphocytic leukemia (SLL) in adults with or without 17p deletion (a specific genetic marker). Venclexta is sometimes used in combination with rituximab to treat these conditions.

Venclexta is also used in combination with azacitidine, decitabine, or cytarabine to treat acute myeloid leukemia. This combination is for use in adults who are 75 years or older, or who cannot use standard chemotherapy due to other medical conditions.

Venclexta is sometimes given after other treatments have failed.