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Corphedra and Maprotiline Hydrochloride

Determining the interaction of Corphedra and Maprotiline Hydrochloride and the possibility of their joint administration.

Check result:

Corphedra <> Maprotiline Hydrochloride

Relevance: 04.04.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Maprotiline may blunt the pressor effect of some sympathomimetics. The mechanism is unknown. Data exist for dopamine, ephedrine, mephentermine, and metaraminol. No special precautions appear to be necessary, except for closer observation.

References

Briant RH, George CF "The assessment of potential drug interactions with a new tricyclic antidepressant drug." Br J Clin Pharmacol 1 (1974): 113-8

Corphedra

Generic Name: ephedrine

Brand name: Akovaz

Synonyms: Corphedra (Intravenous)

What is Corphedra?

Maprotiline Hydrochloride

Generic Name: maprotiline

Brand name: Ludiomil

Synonyms: Maprotiline

What is Maprotiline Hydrochloride?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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