Cotellic and Ismelin

• Generic Name: cobimetinib
• Dosage Forms: tablet, film coated
• Other Brand Names: Cotellic

Cotellic (cobimetinib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Cotellic is used to treat a certain type of metastatic melanoma (skin cancer) that has spread to other parts of the body and cannot be removed with surgery.

Cotellic is usually given together with another medicine called vemurafenib (Zelboraf).

Cotellic is used only if your tumor has a specific genetic marker, for which your doctor will test.

• Generic Name: guanethidine
• Dosage Forms: Tablets
• Other Brand Names:

Guanethidine belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension).

High blood pressure adds to the work load of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Guanethidine works by controlling nerve impulses along certain nerve pathways. As a result, it relaxes the blood vessels so that blood passes through them more easily. This helps to lower blood pressure.

Guanethidine is available only with your doctor's prescription.