Coumadin and Ipilimumab

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using ipilimumab together with warfarin may increase the risk of serious or life-threatening gastrointestinal bleeding complications. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. You should seek immediate medical attention if you if you develop severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR CLOSELY: The concomitant use of ipilimumab and anticoagulants may increase the risk of gastrointestinal hemorrhage. Both drugs have been individually associated with this adverse reaction.

MANAGEMENT: If anticoagulant treatment is required, caution and close monitoring for gastrointestinal bleeding is advisable.

Coumadin

Generic Name: warfarin

Brand name: Coumadin, Jantoven

Synonyms: n.a.

What is Coumadin?

Ipilimumab

Generic Name: ipilimumab

Brand name: Yervoy

Synonyms: n.a.

What is Ipilimumab?