Coumadin and Viva topical

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using warfarin together with methyl salicylate topical. Using warfarin with methyl salicylate topical can cause you to bleed more easily. If you receive treatment with warfarin you should avoid or limit self-medication with these products. Your warfarin levels could be affected by absorption of methyl salicylate topical. Absorption of methyl salicylate topical may be increased with frequent applications; use of large quantities or over large areas of skin; use of ointment-based formulations; and use of covered dressings or heating pads over application areas. You may need a warfarin dose adjustment in addition to testing of your prothrombin time or International Normalized Ratio (INR). Call your doctor promptly if you have any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Methyl salicylate may be absorbed systemically following topical administration and may potentiate the effects of oral anticoagulants. Salicylates interfere with the action of vitamin K and induce a dose-dependent alteration in hepatic synthesis of coagulation factors VII, IX and X, occasionally increasing the prothrombin time. Altered coagulation parameters and/or bleeding have been reported in patients stabilized on warfarin following the use of topical analgesic preparations containing methyl salicylate.

MANAGEMENT: Patients treated with oral anticoagulants should avoid or limit self-medication with these products. Systemic absorption of topical medication may be increased with frequent applications; use of large quantities or over large areas of skin; use of ointment-based formulations; and use of occlusive dressings or heating pads over application areas. Patients should be advised to promptly report any signs of bleeding to their physician, including pain, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools. Patients should also be counseled to avoid any other over-the-counter salicylate products.

Coumadin

Generic Name: warfarin

Brand name: Coumadin, Jantoven

Synonyms: n.a.

What is Coumadin?

Viva topical

Generic Name: camphor / lidocaine / methyl salicylate topical

Brand name: Viva, JointFlex, Original Ointment

Synonyms: Viva (topical)

What is Viva topical?