Coumadin Injection and Precose
Determining the interaction of Coumadin Injection and Precose and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data suggest that the anticoagulant effect of warfarin may be increased in patients also receiving acarbose. The International Normalization Ratio (INR) may increase out of the therapeutic range. The mechanism is not known, but may be related to increased absorption of warfarin. This interaction may occur with other oral anticoagulants although data is lacking. The clinician may consider closer INR and clinical monitoring in patients starting or stopping acarbose therapy while also receiving oral anticoagulants. The dose of the oral anticoagulant may need to be adjusted. Patients should be advised to promptly report any signs of bleeding to their physician, including pain, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools.
- Morreale AP, Janetzky K "Probable interaction of warfarin and acarbose." Am J Health Syst Pharm 54 (1997): 1551-2
Generic Name: warfarin
Brand name: Coumadin, Jantoven
Synonyms: Coumadin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Coumadin Injection-Pred Forte
- Coumadin Injection-Pred Forte ophthalmic
- Coumadin Injection-Pred Mild
- Coumadin Injection-Pred Mild ophthalmic
- Coumadin Injection-Pred-G
- Coumadin Injection-Pred-G ophthalmic
- Precose-Covaryx
- Precose-Covaryx HS
- Precose-Covera-HS
- Precose-Cozaar
- Precose-CPB WC
- Precose-CPM-PSE DM Drops