Coumadin Injection and Trazodone Extended-Release Tablets
Determining the interaction of Coumadin Injection and Trazodone Extended-Release Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One case report has suggested that trazodone may reduce prothrombin and partial thromboplastin times. The mechanism and clinical significance are unknown. Similar effects may occur with other oral anticoagulants. The patient's PT or INR should be observed for alterations. An increase in oral anticoagulant dosage may be necessary. Patients should be advised to promptly report any signs of blood clots (e.g. chest pain, shortness of breath, sudden loss of vision, or pain, redness or swelling in an extremity).
- Hardy JL, Sirois A "Reduction of prothrombin and partial thromboplastin times with trazodone." Can Med Assoc J 135 (1986): 1372
Generic Name: warfarin
Brand name: Coumadin, Jantoven
Synonyms: Coumadin
Generic Name: trazodone
Brand name: Desyrel, Desyrel Dividose, Oleptro
Synonyms: Trazodone, TraZODone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Coumadin Injection-Trazodone Hydrochloride
- Coumadin Injection-Trazodone Oral
- Coumadin Injection-Trazodone Tablets
- Coumadin Injection-Treanda
- Coumadin Injection-Trecator
- Coumadin Injection-Trecator-SC
- Trazodone Extended-Release Tablets-Covaryx
- Trazodone Extended-Release Tablets-Covaryx HS
- Trazodone Extended-Release Tablets-Covera-HS
- Trazodone Extended-Release Tablets-Cozaar
- Trazodone Extended-Release Tablets-CPB WC
- Trazodone Extended-Release Tablets-CPM-PSE DM Drops