Coumadin Injection and Viagra
Determining the interaction of Coumadin Injection and Viagra and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using warfarin together with sildenafil may cause you to bleed more easily. You may need a dose adjustment based on your prothrombin time or International Normalized Ratio (INR). Call your doctor promptly if you have any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of sildenafil with oral vitamin K antagonists in patients with pulmonary arterial hypertension has been associated with an increased risk of bleeding (primarily epistaxis) compared to administration without oral vitamin K antagonists. The incidence of epistaxis was 9% with oral vitamin K antagonists versus 2% with placebo.
MANAGEMENT: Caution is advised in patients with pulmonary arterial hypertension receiving sildenafil and oral vitamin K antagonists. The INR should be checked frequently and patients should be advised to promptly report any signs of bleeding to their physician, including pain, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Revatio (sildenafil)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
Generic Name: warfarin
Brand name: Coumadin, Jantoven
Synonyms: Coumadin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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