Crixivan and Didanosine

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using didanosine together with indinavir may decrease the effects of indinavir. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

ADJUST DOSING INTERVAL: Concurrent administration of didanosine may decrease the bioavailability of indinavir, since indinavir requires normal gastric pH for optimal absorption and didanosine is formulated with buffer agents that decrease gastric pH.

MANAGEMENT: If concomitant therapy is desired, the two medications should be taken at least one hour apart on an empty stomach.

Crixivan

Generic Name: indinavir

Brand name: Crixivan

Synonyms: n.a.

What is Crixivan?

Didanosine

Generic Name: didanosine

Brand name: Videx, Videx EC

Synonyms: n.a.

What is Didanosine?