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Crixivan and Fluconazole

Determining the interaction of Crixivan and Fluconazole and the possibility of their joint administration.

Check result:

Crixivan <> Fluconazole

Relevance: 25.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration of fluconazole has been shown to decrease the area under the plasma concentration-time curve of indinavir by 19%. Indinavir did not affect the plasma concentration of fluconazole. No mechanism has been proposed for this interaction. Adjustments in indinavir dosage are not likely to be necessary.

References

"Product Information. Crixivan (indinavir)." Merck & Co, Inc, West Point, PA.

Crixivan

Generic Name: indinavir

Brand name: Crixivan

Synonyms: n.a.

What is Crixivan?

Fluconazole

Generic Name: fluconazole

Brand name: Diflucan

Synonyms: n.a.

What is Fluconazole?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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