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Crixivan and Sulfatrim Pediatric

Determining the interaction of Crixivan and Sulfatrim Pediatric and the possibility of their joint administration.

Check result:

Crixivan <> Sulfatrim Pediatric

Relevance: 25.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

When indinavir was given concomitantly with trimethoprim/sulfamethoxazole DS (TMP/SMX 160/800 mg) for one week, a 19% increase was observed in the area under the plasma concentration-time curve of trimethoprim. The plasma concentrations of sulfamethoxazole and indinavir were not affected. This interaction is unlikely to be of clinical importance, although it may be appropriate to monitor the patient for trimethoprim-related toxicities.

References

"Product Information. Crixivan (indinavir)." Merck & Co, Inc, West Point, PA.

Crixivan

Generic Name: indinavir

Brand name: Crixivan

Synonyms: n.a.

What is Crixivan?

Sulfatrim Pediatric

Generic Name: sulfamethoxazole / trimethoprim

Brand name: Bactrim, Bactrim DS, Bactrim IV, Septra IV, SMZ-TMP DS, Sulfatrim Pediatric, Septra, Sulfatrim, Bethaprim, Cotrim, Uroplus, Uroplus DS, Cotrim DS, Bactrim Pediatric, Bethaprim Pediatric, Sulfatrim Suspension, Cotrim Pediatric, Septra DS

Synonyms: Sulfatrim Pediatric (Oral)

What is Sulfatrim Pediatric?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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