Cromolyn Inhalation, oral/nebulization and Dorzolamide Hydrochloride

• Generic Name: cromolyn
• Dosage Forms: n.a.
• Other Brand Names: Gastrocrom

Cromolyn is used to prevent the symptoms of asthma. When it is used regularly, cromolyn lessens the number and severity of asthma attacks by reducing inflammation in the lungs. Cromolyn is also used just before exposure to conditions or substances (for example, exercise, allergens, such as pollen, aspirin, chemicals, cold air, or air pollutants) that cause bronchospasm (wheezing or difficulty in breathing). Cromolyn will not help an asthma or bronchospasm attack that has already started.

Cromolyn may be used alone or with other asthma medicines, such as bronchodilators (medicines that open up narrowed breathing passages) or corticosteroids (cortisone-like medicines).

Cromolyn inhalation works by acting on certain inflammatory cells in the lungs to prevent them from releasing substances that cause asthma symptoms or bronchospasm.

Cromolyn is available only with your doctor's prescription.

It is very important that you read and understand the following information. If any of it causes you special concern, check with your doctor. Also, if you have any questions or if you want more information about cromolyn or your medical problem, ask your doctor, nurse, or pharmacist.

• Generic Name: dorzolamide ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Trusopt

Reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Fixed-combination preparation containing dorzolamide and timolol (Cosopt) used topically to reduce elevated IOP in patients with open-angle glaucoma or ocular hypertension who have not responded adequately (i.e., failed to achieve target IOP as determined after multiple measurements over time) to a topical β-adrenergic blocking agent. Fixed-combination preparation associated with slightly smaller decrease in IOP than combination therapy with dorzolamide (administered 3 times daily) and timolol (administered twice daily).

A first-line “add-on” agent when more than one drug is needed. Add-on therapy with dorzolamide to existing timolol therapy is as effective and better tolerated than add-on therapy with pilocarpine.

Safety and efficacy not established for the treatment of acute angle-closure glaucoma.

Used prophylactically before neodymium yttrium aluminum garnet (Nd:YAG) laser posterior capsulotomy.

Administration of 1 drop (20 µL) of dorzolamide 2% 1 hour prior to capsulotomy is more effective in preventing postoperative increases in IOP than placebo and as effective as oral acetazolamide 125 mg administered 1 hour prior to the procedure.