Crysvita and Etelcalcetide
Determining the interaction of Crysvita and Etelcalcetide and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using burosumab together with etelcalcetide may cause a condition known as hypocalcemia, or low blood calcium. Symptoms of hypocalcemia include numbness or tingling around your mouth, muscle spasms, convulsions, mental changes (irritability, depression, psychosis), increased pressure on the brain, and irregular heartbeat. Let your doctor know if you experience these or other unusual symptoms. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of burosumab with calcimimetic drugs, such as cinacalcet, may potentially exacerbate hypocalcemia. The mechanism for this interaction has not been delineated.
MANAGEMENT: Until further information is available, caution is advised when combining burosumab with calcimimetic drugs.
- EMA. European Medicines Agency. European Union "EMA - List of medicines under additional monitoring. Available from: URL: http://www.ema.europa.eu/ema/index.jsp?curl=pages/regulation/document_listing/document_listing_000366.jsp&mid=WC0b01ac058067c852" ([2013 - ]):
Generic Name: etelcalcetide
Brand name: Parsabiv
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Crysvita-Etelcalcetide Hydrochloride
- Crysvita-Etelcalcetide Intravenous
- Crysvita-Eth-Oxydose
- Crysvita-Ethacrynate Sodium
- Crysvita-Ethacrynate Sodium Injection
- Crysvita-Ethacrynate sodium Intravenous
- Etelcalcetide-Cubicin
- Etelcalcetide-Cubicin RF
- Etelcalcetide-Cubicin, Cubicin RF
- Etelcalcetide-Cuprimine
- Etelcalcetide-Curad Triple Antibiotic
- Etelcalcetide-CureChrome