Cubicin, Cubicin RF and Sunitinib Malate

• Generic Name: daptomycin
• Dosage Forms: n.a.
• Other Brand Names: Cubicin, Cubicin RF

Treatment of complicated skin and skin structure infections caused by susceptible Staphylococcus aureus (including methicillin-resistant S. aureus [MRSA; also known as oxacillin-resistant S. aureus or ORSA]), Streptococcus pyogenes (group A β-hemolytic streptococci, GAS), S. agalactiae (group B streptococci, GBS), S. dysgalactiae subsp. equisimilis, and Enterococcus faecalis (vancomycin-susceptible strains only).

Bacteremia and Endocarditis

Treatment of bacteremia (blood stream infection) caused by susceptible S. aureus (including MRSA).

Also used for treatment of S. aureus bacteremia in patients with right-sided infective endocarditis. Efficacy not established in patients with left-sided infective endocarditis caused by S. aureus; limited data suggest a poor outcome in such patients despite daptomycin treatment.

Not studied in patients with prosthetic valve endocarditis.

• Generic Name: sunitinib
• Dosage Forms: n.a.
• Other Brand Names: Sutent

Treatment of GIST in adults who are intolerant of or whose disease has progressed during imatinib therapy.

Treatment of advanced renal cell carcinoma.

Treatment of progressive, well-differentiated PNET in patients with unresectable, locally advanced, or metastatic disease.