Cyanocobalamin (B12) Capsules and Tablets and Famotidine and ibuprofen
Determining the interaction of Cyanocobalamin (B12) Capsules and Tablets and Famotidine and ibuprofen and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:H2 antagonists may alter the disposition of nonsteroidal anti-inflammatory drugs (NSAIDs), resulting in increased or decreased plasma concentrations. Data are varied, even for the same NSAID. The mechanism may be related to inhibition of metabolism, changes in gastric pH that decrease absorption, and/or reduced urinary elimination. Statistically significant changes have been small and of limited clinical significance. Clinical monitoring of patient response and tolerance is recommended.
- Scavone JM, Greenblatt DJ, Matlis R, Harmatz JS "Interaction of oxaprozin with acetaminophen, cimetidine, and ranitidine." Eur J Clin Pharmacol 31 (1986): 371-4
- Said SA, Foda AM "Influence of cimetidine on the pharmacokinetics of piroxicam in rat and man." Arzneimittelforschung 39 (1989): 790-2
- "Product Information. Daypro (oxaprozin)." Searle, Skokie, IL.
Generic Name: cyanocobalamin
Brand name: Cobolin-M, Depo-Cobolin, Vitamin B12, B-12 Dots, Nascobal, Cobal 1000, Vitamin B-12
Synonyms: Vitamin B12 Injection, Cyanocobalamin
Generic Name: famotidine / ibuprofen
Brand name: Duexis
Synonyms: Ibuprofen and Famotidine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cyanocobalamin (B12) Capsules and Tablets-Famotidine Chewable Tablets
- Cyanocobalamin (B12) Capsules and Tablets-Famotidine Injection
- Cyanocobalamin (B12) Capsules and Tablets-Famotidine Injection Solution
- Cyanocobalamin (B12) Capsules and Tablets-Famotidine Oral Suspension
- Cyanocobalamin (B12) Capsules and Tablets-Famotidine Tablets
- Cyanocobalamin (B12) Capsules and Tablets-Famotidine, Calcium Carbonate, and Magnesium Hydroxide
- Famotidine and ibuprofen-Cyanocobalamin (B12) Chewable Tablets
- Famotidine and ibuprofen-Cyanocobalamin (B12) Extended-Release Tablets
- Famotidine and ibuprofen-Cyanocobalamin (B12) Injection
- Famotidine and ibuprofen-Cyanocobalamin (B12) Liquid
- Famotidine and ibuprofen-Cyanocobalamin (B12) Lozenge and Oral-Disintegrating Tablet (ODT)
- Famotidine and ibuprofen-Cyanocobalamin (B12) Nasal Spray