Cyclophosphamide Tablets and Gliadel

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using carmustine together with cyclophosphamide may increase the effects of carmustine. Contact your doctor if you experience extreme fatigue, unusual easy bruising or bleeding; black, bloody or tarry stools, fever, chills, sore throat, and lung or breathing problems. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Limited animal data and limited observations of humans suggest that cyclophosphamide and/or cisplatin may increase plasma carmustine (BCNU) levels. It is suspected that cisplatin can decrease the metabolism of BCNU. Blood BCNU levels are positively correlated with a steroid-responsive pulmonary injury seen in patients treated with BCNU, and pretreatment or concomitant therapy with cyclophosphamide and/or cisplatin may increase the risk.

MANAGEMENT: Close monitoring for signs of pulmonary toxicity is recommended during treatment.

Cyclophosphamide Tablets

Generic Name: cyclophosphamide

Brand name: Cytoxan, Neosar, Cytoxan Lyophilized

Synonyms: Cyclophosphamide (oral and injection), Cyclophosphamide

What is Cyclophosphamide Tablets?

Gliadel

Generic Name: carmustine

Brand name: BiCNU, Gliadel

Synonyms: n.a.

What is Gliadel?