Cyclophosphamide Tablets and Modafinil

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

The concomitant use of modafinil may theoretically alter the metabolic activation and inactivation of ifosfamide and cyclophosphamide. Modafinil is a modest CYP450 2B6 and 3A4 inducer in vitro. Ifosfamide and cyclophosphamide are substrates of these isoenzymes. If these drugs are to be used together, close monitoring of the patient for altered efficacy and safety is recommended.

Cyclophosphamide Tablets

Generic Name: cyclophosphamide

Brand name: Cytoxan, Neosar, Cytoxan Lyophilized

Synonyms: Cyclophosphamide (oral and injection), Cyclophosphamide

What is Cyclophosphamide Tablets?

Modafinil

Generic Name: modafinil

Brand name: Provigil

Synonyms: n.a.

What is Modafinil?