Cyclosporine Capsules and Xyrem

• Generic Name: cyclosporine
• Dosage Forms: capsule, liquid filled
• Other Brand Names: Gengraf, Neoral, Sandimmune, Sandimmune

Cyclosporine weakens your body's immune system, to help keep it from "rejecting" a transplanted organ such as a kidney. Organ rejection happens when the immune system treats the new organ as an invader and attacks it.

Cyclosporine is used to prevent organ rejection after a kidney, heart, or liver transplant.

Cyclosporine is also used to treat severe psoriasis or severe rheumatoid arthritis.

Cyclosporine may also be used for purposes not listed in this medication guide.

• Generic Name: sodium oxybate
• Dosage Forms: oral solution
• Other Brand Names: Xyrem

Xyrem (sodium oxybate) is a central nervous system depressant. It is used to treat cataplexy (sudden loss of muscle strength) and reduce daytime sleepiness in patients with narcolepsy.

Xyrem is also known as GHB, a known street drug of abuse. Because of the potential for abuse and the serious side effects that may occur, Xyrem is available only from a certified pharmacy under a special program called Xyrem REMS Program. Your doctor must be registered in the program in order to prescribe this medicine for you.