Cyclosporine Capsules, Modified and Valacyclovir Hydrochloride
Determining the interaction of Cyclosporine Capsules, Modified and Valacyclovir Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:ValACYclovir can sometimes cause damage to the kidneys, and using it with other medications that can also affect the kidneys such as cycloSPORINE may increase that risk. Symptoms of kidney damage include swelling, weight gain, shortness of breath, drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea, vomiting, pain in your lower back, and urinating more or less than usual or not at all. Let your doctor know if you develop some or all of these symptoms during treatment with these medications. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concurrent use of valaciclovir with other nephrotoxic drugs may increase the risk of renal toxicity. Patients who are elderly, debilitated, dehydrated, or who have preexisting renal dysfunction may have a higher risk of developing adverse reactions. Cases of acute renal failure have been reported.
MANAGEMENT: Close clinical and laboratory monitoring of renal function and drug serum concentrations (if clinically appropriate) is recommended.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Valtrex (valacyclovir)." Glaxo Wellcome, Research Triangle Park, NC.
Generic Name: cyclosporine
Brand name: Gengraf, Neoral, Sandimmune, Sandimmune
Synonyms: Cyclosporine (oral/injection), CycloSPORINE (Systemic)
Generic Name: valacyclovir
Brand name: Valtrex
Synonyms: Valacyclovir, ValACYclovir
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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