Cyclosporine Capsules, Modified and Vibramycin Hyclate
Determining the interaction of Cyclosporine Capsules, Modified and Vibramycin Hyclate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Doxycycline may increase cyclosporine serum concentrations by an unknown mechanism. Data are from a single unpublished case report in which the effects were reproduced upon rechallenge with doxycycline. Until more data are available, caution should be used with concomitant administration of these agents.
- Cockburn IT, Krupp P "An appraisal of drug interactions with sandimmun." Transplant Proc 21 (1989): 3845-50
- Cockburn I "Cyclosporine A: a clinical evaluation of drug interactions." Transplant Proc 18 (1986): 50-5
Generic Name: cyclosporine
Brand name: Gengraf, Neoral, Sandimmune, Sandimmune
Synonyms: Cyclosporine (oral/injection), CycloSPORINE (Systemic)
Generic Name: doxycycline
Brand name: Acticlate, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Mondoxyne NL, Monodox, Morgidox, Oracea, Oraxyl, Periostat Targadox, Vibramycin Calcium, Vibramycin Hyclate, Vibramycin monohydrate, Vibra-Tabs, Adox Pak 2/100, Adoxa, Adoxa Pak 1/100, Adoxa Pak 1/150, Avidoxy, TargaDOX, Vibramycin, Doxy 100, TargaDOX
Synonyms: Doxycycline
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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