Cyproheptadine Solution and Metopirone
Determining the interaction of Cyproheptadine Solution and Metopirone and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using metyraPONE together with cyproheptadine. Using these medications together may cause metyraPONE to be less effective. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The effect of metyrapone is diminished in patients concurrently receiving cyproheptadine, which may alter ACTH function test results. The mechanism is unknown, but may involve the antiserotonergic effect of cyproheptadine.
MANAGEMENT: Cyproheptadine should be discontinued before a metyrapone test is administered.
- Plonk J, Feldman JM "Modification of adrenal function by the anti-serotonin agent cyproheptadine." J Clin Endocrinol Metab 42 (1975): 291-5
- Plonk J, Feldman JM "Adrenal function in the carcinoid syndrome: effects of the serotonin antagonist cyproheptadine." Metabolism 24 (1975): 1035-46
Generic Name: cyproheptadine
Brand name: Periactin
Synonyms: Cyproheptadine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Cyproheptadine Solution-Metoprolol Extended-Release Capsules
- Cyproheptadine Solution-Metoprolol Extended-Release Tablets
- Metopirone-Cyproheptadine Syrup
- Metopirone-Cyproheptadine Tablets
- Metopirone-Cyramza
- Metopirone-Cyred
- Metopirone-Cyred EQ
- Metopirone-Cysto-Conray II