Cytadren and DexPak 6 DayTaperpak

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using dexamethasone together with aminoglutethimide. Using these medications together may cause dexamethasone to be less effective. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Aminoglutethimide may significantly increase dexamethasone clearance by induction of CYP450 3A4 hepatic microsomal enzymes. An increase of 292% in dexamethasone clearance has been reported. It is unknown whether other corticosteroids would be affected to the same extent.

MANAGEMENT: Dexamethasone should not be used in patients receiving aminoglutethimide for adrenal suppression. If glucocorticoid replacement is necessary, hydrocortisone is recommended as an alternative because it does not appear to interact.

Cytadren

Generic Name: aminoglutethimide

Brand name:

Synonyms: Cytadren (Oral)

What is Cytadren?

DexPak 6 DayTaperpak

Generic Name: dexamethasone

Brand name: Baycadron, Dexamethasone Intensol, DexPak 10 Day Taperpak, DexPak 13 DayTaperpak, DexPak 6 DayTaperpak, De-Sone LA, Dexacen-4, Dexasone, Dexasone LA, Solurex, Solurex LA, Decadron, DexPak, TaperDex, Zema-Pak, ZoDex, Zonacort

Synonyms: DexPak 10 Day Taperpak, DexPak 10 Day TaperPak

What is DexPak 6 DayTaperpak?