Cytomel and Rifampin Capsules

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this interaction is not currently available.MONITOR: Rifampin may decrease exogenous levothyroxine plasma concentrations resulting in elevated thyroid stimulating hormone (TSH) and exacerbation of hypothyroidism. The mechanism may be induction of hepatic CYP450 enzymes responsible for levothyroxine metabolism. Liothyronine may be similarly affected. MANAGEMENT: Clinical monitoring of patient response, including laboratory serum TSH concentrations, is recommended. Adjustment of thyroid hormone dosage may be indicated when initiating or discontinuing rifampin therapy. References "Product Information. Rifadin (rifampin)." Hoechst Marion-Roussel Inc, Kansas City, MO. Nolan SR, Self TH, Norwood JM "Interaction between rifampin and levothyroxine." South Med J 92 (1999): 529-31 Cerner Multum, Inc. "Australian Product Information." O 0 Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 View all 4 references

MONITOR: Rifampin may decrease exogenous levothyroxine plasma concentrations resulting in elevated thyroid stimulating hormone (TSH) and exacerbation of hypothyroidism. The mechanism may be induction of hepatic CYP450 enzymes responsible for levothyroxine metabolism. Liothyronine may be similarly affected.

MANAGEMENT: Clinical monitoring of patient response, including laboratory serum TSH concentrations, is recommended. Adjustment of thyroid hormone dosage may be indicated when initiating or discontinuing rifampin therapy.

Cytomel

Generic Name: liothyronine

Brand name: Cytomel, Triostat

Synonyms: n.a.

What is Cytomel?

Rifampin Capsules

Generic Name: rifampin

Brand name: Rifadin, Rifadin IV, Rimactane

Synonyms: Rifampin

What is Rifampin Capsules?