Cytomel and Tegretol (Carbamazepine Chewable Tablets)

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using carBAMazepine together with liothyronine can decrease the effects of liothyronine. This can cause fatigue, weight gain, constipation, and low blood pressure. Talk with your doctor before using carBAMazepine while you are using liothyronine. You may need a dose adjustment and may need to check your thyroid levels more often. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Carbamazepine and phenytoin may decrease exogenous thyroid plasma concentrations resulting in elevated thyroid stimulating hormone (TSH) and possible exacerbation of hypothyroidism. The mechanism may be induction of hepatic CYP450 enzymes responsible for thyroxine (T4) and triiodothyronine (T3) metabolism. In addition, T3 and T4 may be displaced from thyroxine binding globulin by phenytoin. Clinical data are limited.

MANAGEMENT: Clinical monitoring of patient response, including laboratory serum TSH concentrations, is recommended. Adjustment of the thyroid replacement dosage may be indicated when initiating or discontinuing phenytoin or carbamazepine therapy.

Cytomel

Generic Name: liothyronine

Brand name: Cytomel, Triostat

Synonyms: n.a.

What is Cytomel?

Tegretol (Carbamazepine Chewable Tablets)

Generic Name: carbamazepine

Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Synonyms: Tegretol

What is Tegretol (Carbamazepine Chewable Tablets)?