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Cytomel and Trazodone Hydrochloride

Determining the interaction of Cytomel and Trazodone Hydrochloride and the possibility of their joint administration.

Check result:

Cytomel <> Trazodone Hydrochloride

Relevance: 04.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

A small series of cases has suggested that exogenous thyroid hormones may potentiate the antidepressant actions of trazodone. The mechanism of the interaction has not been completely elucidated.

References

Browne JL, Rice JL, Evans DL, Prange AJ "Triiodothyronine augmentation of the antidepressant effect of the nontricyclic antidepressant trazodone." J Nerv Ment Dis 178 (1990): 598-9

Cytomel

Generic Name: liothyronine

Brand name: Cytomel, Triostat

Synonyms: n.a.

What is Cytomel?

Trazodone Hydrochloride

Generic Name: trazodone

Brand name: Desyrel, Desyrel Dividose, Oleptro

Synonyms: Trazodone, TraZODone

What is Trazodone Hydrochloride?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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