Cytoxan and Ondansetron Tablets
Determining the interaction of Cytoxan and Ondansetron Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data have shown that ondansetron may significantly decrease the area under the plasma concentration-time curve (AUC) for cyclophosphamide. Theoretically, this interaction could decrease the pharmacologic effect of cyclophosphamide, but, clinically, the significance of this interaction is not known. More data are needed.
- Gilbert CJ, Petros WP, Cavanaugh C, et al. "Influence of ondansetron (OND) on the pharmacokinetics (PK) of high dose cyclophosphamide (CPA) (Meeting abstract)." Proc Annu Meet Am Soc Clin Oncol 14 (1995): a9311995
Generic Name: cyclophosphamide
Brand name: Cytoxan, Neosar, Cytoxan Lyophilized
Synonyms: Cytoxan (Injection)
Generic Name: ondansetron
Brand name: Zofran, Zofran ODT, Zuplenz
Synonyms: Ondansetron
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cytoxan-One A Day Cholesterol Plus
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- Cytoxan-One A Day Essential
- Cytoxan-One A Day Kids Jolly Rancher Gummies
- Cytoxan-One A Day Kids Jolly Rancher Sour Gummies
- Cytoxan-One A Day Kids Scooby-Doo! Complete
- Ondansetron Tablets-Cytoxan (Cyclophosphamide Injection)
- Ondansetron Tablets-Cytoxan (Cyclophosphamide Tablets)
- Ondansetron Tablets-Cytoxan Lyophilized
- Ondansetron Tablets-Cytra K Oral Solution
- Ondansetron Tablets-Cytra-2
- Ondansetron Tablets-Cytra-2 Oral Solution