Dabigatran and Tibsovo

• Generic Name: dabigatran
• Dosage Forms: n.a.
• Other Brand Names: Pradaxa

Dabigatran is used to lower the risk of stroke caused by a blood clot in people with a heart rhythm disorder called atrial fibrillation. dabigatran is used when the atrial fibrillation is not caused by a heart valve problem.

Dabigatran is also used after hip replacement surgery to prevent a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism).

Dabigatran is also used to treat DVT or pulmonary embolism (PE), and to lower your risk of having a repeat DVT or PE.

Dabigatran may also be used for purposes not listed in this medication guide.

• Generic Name: ivosidenib
• Dosage Forms: tablet, film coated
• Other Brand Names: Tibsovo

Tibsovo (ivosidenib) targets a specific gene mutation called IDH1, which can affect your bone marrow. IDH1 mutation prevents young blood cells from developing into healthy adult blood cells, which can result in symptoms of acute myeloid leukemia.

Tibsovo is used to treat acute myeloid leukemia (AML).

Tibsovo is used to treat AML in adults with an IDH1 mutation. Your doctor will test you for this gene. Ivosidenib is used when other treatments did not work or have stopped working.

Tibsovo is also used in adults 75 years and older who have newly-diagnosed AML and cannot use certain chemotherapy treatments because of other health problems.