Daclatasvir Dihydrochloride and TriLyte with Flavor Packs

• Generic Name: daclatasvir
• Dosage Forms: n.a.
• Other Brand Names: Daklinza

Treatment of chronic HCV genotype 1 or genotype 3 infection in treatment-naive (previously untreated) or previously treated adults, including those with cirrhosis (compensated or decompensated), liver transplant recipients, and those with HIV coinfection.

Treatment of chronic HCV genotype 2 or genotype 4 infection; only limited data available.

Must be used in conjunction with other antivirals; do not use alone.

Usually used in a multiple-drug regimen that includes sofosbuvir (with or without ribavirin).

Efficacy of daclatasvir and sofosbuvir (with or without ribavirin) for treatment of HCV genotype 1a infection is reduced in cirrhotic patients with NS5A polymorphisms M28, Q30, L31, or Y93 at baseline. Consider screening for NS5A polymorphisms prior to initiation of treatment in cirrhotic patients with HCV genotype 1a infection. (See General under Dosage and Administration.)

Efficacy of daclatasvir and sofosbuvir (with or without ribavirin) is reduced in cirrhotic patients with HCV genotype 3 infection compared with those without cirrhosis.

Treatment of chronic HCV infection is complex and rapidly evolving; consult a specialist to obtain the most up-to-date information.

• Generic Name: polyethylene glycol 3350 with electrolytes
• Dosage Forms: powder for oral solution
• Other Brand Names: Colyte with Flavor Packs, GaviLyte-C, GoLYTELY, MoviPrep, NuLYTELY Orange, NuLYTELY with Flavor Packs, PEG-3350 with Electolytes, Plenvu, TriLyte with Flavor Packs, NuLYTELY, TriLyte, Suclear

TriLyte with Flavor Packs is a laxative solution that stimulates bowel movements. This medication also contains minerals to replace electrolytes that are passed from the body in the stool.

TriLyte with Flavor Packs is used to clean the bowel before colonoscopy, a barium x-ray, or other intestinal procedures.

TriLyte with Flavor Packs may also be used for purposes not listed in this medication guide.