Dantrolene Sodium and Vecuronium
Determining the interaction of Dantrolene Sodium and Vecuronium and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using vecuronium together with dantrolene can prolong the effects of vecuronium. You should be closely monitored for prolong breathing cessation and respiratory paralysis after use of dantrolene. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant or sequential administration of dantrolene and vecuronium may potentiate and prolong neuromuscular blockade. Data have been conflicting; cases of uneventful coadministration have also been reported.
MANAGEMENT: Monitoring patients for excessive or prolonged neuromuscular blockade may be advisable.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Multum Information Services, Inc. Expert Review Panel"
Generic Name: dantrolene
Brand name: Dantrium, Dantrium Intravenous, Revonto, Ryanodex
Synonyms: Dantrolene
Generic Name: vecuronium
Brand name: Vecuronium Bromide, Norcuron
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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