Dapsone and Tylenol Cold

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Talk to your doctor before using acetaminophen together with dapsone. Acetaminophen can cause a condition called methemoglobinemia that reduces the oxygen-carrying capacity of the blood to different organs, and combining the medication with dapsone may increase the risk. Infants and patients with certain conditions such as glucose-6-phosphate dehydrogenase deficiency or anemia are more likely to develop this condition. You should seek immediate medical attention if you notice signs and symptoms such as a gray discoloration of the skin, mouth, or nail bed; nausea; headache; dizziness; lightheadedness; fatigue; shortness of breath; rapid or shallow breathing; a rapid heartbeat; anxiety; and confusion. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration of oral or topical dapsone with other agents associated with methemoglobinemia may have additive effects and theoretically increase the risk of drug-induced methemoglobinemia. Oral and topical dapsone have been associated with methemoglobinemia, and the risk is increased in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency or congenital or idiopathic methemoglobinemia.

MANAGEMENT: Concurrent use of oral or topical dapsone with other methemoglobinemia-inducing medications should be followed with monitoring for signs and symptoms of methemoglobinemia (e.g., cyanosis, hypoxia).

Dapsone

Generic Name: dapsone

Brand name:

Synonyms: Dapsone (Systemic)

What is Dapsone?

Tylenol Cold

Generic Name: acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine

Brand name: Alka-Seltzer Plus-D Sinus/Cold, Cold Symptoms Relief Maximum Strength, EQ Cold Relief Complete, EQ Cold/Cough Plus, EQL Pain Relief/Cold, Tylenol Cold and Flu Powder, Theraflu Flu, Cold and Cough Powder, Theraflu Nightime Maximum Strength, Comtrex Day and Night, Theraflu Night Cough and Cold and Flu, Co-Apap, Vicks Formula 44M, Cough Formula M Multi-Symptom, Mapap Cold, Child Tylenol Cold Multi-Symptom Plus Cough, Comtrex Cold and Flu Maximum Strength Liquid, Genacol Maximum Strength, Robitussin Honey Flu Nighttime, Children's Tylenol Flu, Alka-Seltzer Plus Cough and Cold Liquigel, Tylenol Cold Complete Formula, Children's Tylenol Cold Plus Cough, Contac Cold and Flu Maximum Strength, Triaminic Flu, Cough & Fever, Theraflu Cold & Cough, Theraflu Severe Cold & Congestion, Theraflu Flu & Cough, Tylenol Cold Day/Night Convenience Pack, Children’s Non-Aspirin Cold/Cough, EQL Pain Relief Plus Cold/Cough, Tylenol Children’s Cold/Cough

Synonyms: n.a.

What is Tylenol Cold?